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Lysosomal Enzyme Release from Guinea Pig Polymorphonuclear Leukocytes by Influenza Virus
https://hiroshima.repo.nii.ac.jp/records/2013155
https://hiroshima.repo.nii.ac.jp/records/201315577fb10e2-cd0f-4279-baa2-9deac23da263
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_36_249.pdf (945.7 KB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Lysosomal Enzyme Release from Guinea Pig Polymorphonuclear Leukocytes by Influenza Virus | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
KIYOTANI, Katsuhiro
× KIYOTANI, Katsuhiro
× TAKEI, Naomi
× MATSUO, Yoshiyasu
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| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Influenza virus | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Lysosomal enzyme release | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Myeloperoxidase | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | NDC | |||||||||||
| 主題 | 490 | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述 | Extracellular release and subsequent decrease of intracellular lysosomal enzymes of guinea pig polymorphonuclear leukocytes (PMNLs) by influenza virus were observed. Total enzyme activity was also decreased in all the enzymes assayed. After incubation of the PMNLs with influenza virus at 37°C for 20 min, the degree in decrease of total enzyme activity varied from enzyme to enzyme: 50% in myeloperoxidase (MPO), 20% in acid phosphatase, 10% in N-Ac-β-glucosaminidase and β-glucuronidase and 5% in lysozyme, respectively. Since MPO assumed to play a critical role in chemiluminescent response of luminol-enhanced system, the dysfunction in oxidative metabolism of PMNLs induced by influenza virus seems to be attributed to intraphagosomal and/or extracellular inactivation of MPO of PMNLs during the process of direct stimulation of respiratory burst. | |||||||||||
| 言語 | en | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Hiroshima Journal Medical Press | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 関連情報 | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 2820906 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0018-2052 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00664312 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 249 | |||||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 36, 号 2, p. 249-255, 発行日 1987-06 |
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| 旧ID | 49985 | |||||||||||
