WEKO3
アイテム
Synergistic Antitumor Effects of Natural Human Tumor Necrosis Factor and Mouse Interferon Beta and Gamma
https://hiroshima.repo.nii.ac.jp/records/2013151
https://hiroshima.repo.nii.ac.jp/records/20131517eee6937-5004-4b0d-84aa-ebffa08a6cd0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
|
|
| Item type | デフォルトアイテムタイプ_(フル)(1) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||||
| タイトル | ||||||||||||
| タイトル | Synergistic Antitumor Effects of Natural Human Tumor Necrosis Factor and Mouse Interferon Beta and Gamma | |||||||||||
| 言語 | en | |||||||||||
| 作成者 |
ITANO, Satoshi
× ITANO, Satoshi
× FUCHIMOTO, Sadanori
× ORITA, Kunzo
|
|||||||||||
| アクセス権 | ||||||||||||
| アクセス権 | open access | |||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | TNF | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Interferon | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Synergistic effect | |||||||||||
| 主題 | ||||||||||||
| 主題Scheme | NDC | |||||||||||
| 主題 | 490 | |||||||||||
| 内容記述 | ||||||||||||
| 内容記述 | Referring to synergistic antitumor effects of natural human tumor necrosis factor (n-TNF) derived from human acute lymphoblastic leukemia BALL-I cell as well as mouse interferon beta (mIFNbeta) and mouse interferon gamma (mIFNgamma), a series of the study was made using Lewis lung carcinoma grafted on BDF1 mice. With a combination dose of n-TNF (1 x 10^2 U/kg/day) and mIFNbeta (1 x 10^2 IU/kg/day) as well as that of n-TNF (1 x 10^2 U/kg/day) and mIFNgamma (1 x 10^2 IU/kg/day), a significant enhancement of antitumor effect was observed. Furthermore, with a triple combination dose of n-TNF (1 x 10^2 U/kg/day), mIFNbeta (I x 10^2 IU/kg/day) and mIFNgamma (I x 10^2 IU/kg/day), too, a strong synergistic effect was noted. The concentration of n-TNF required for concomitant use with mIFNbeta and mIFNgamma was 1 over 5 x 10^3 of that required for single dose of n-TNF, to obtain the same level of effect. | |||||||||||
| 言語 | en | |||||||||||
| 出版者 | ||||||||||||
| 出版者 | Hiroshima Journal Medical Press | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 関連情報 | ||||||||||||
| 識別子タイプ | PMID | |||||||||||
| 関連識別子 | 2443470 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0018-2052 | |||||||||||
| 収録物識別子 | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00664312 | |||||||||||
| 開始ページ | ||||||||||||
| 開始ページ | 219 | |||||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 36, 号 2, p. 219-225, 発行日 1987-06 |
|||||||||||
| 旧ID | 49981 | |||||||||||