| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Cellular Immune Competence of Patients with Lung Cancer and Other Lung Diseases. I. Analysis of peripheral blood lymphocyte subsets using monoclonal antibodies |
|
言語 |
en |
| 作成者 |
FUJIWARA, Saeko
AKIYAMA, Mitoshi
KOBUKE, Kyoko
ICHIMARU, Shinichiro
TAKAISHI, Masatoshi
INAMIZU, Tsutomu
KOHNO, Nobuoki
TAKAMI, Shunsuke
NOUMI, Kazumasa
KAWAMOTO, Masahide
YAMAKIDO, Michio
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Lung cancer |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Lymphocyte subsets |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Monoclonal antibody |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Lymphocyte subsets and lymphocyte responsiveness to mitogens were examined for patients with lung disease and healthy people. The results are as follows: 1) Lymphocytes derived from healthy persons showed an age dependent increase in the percentage of Leu-7+ cells and a decrease in reactivity to phytohemagglutinin (PHA). The percentage of Leu-1+ and Leu-3a+ cells was higher in females than in males under 30 years of age, while the percentage of Leu-7+ cells was higher in males at all ages. 2) Untreated lung cancer patients showed decreases in the percentage of Leu-1+ cells and reactivity to PHA and concanavalin A (Con A), and an increase in the percentage of Leu-11a+ cells. 3) No difference in lymphocyte subsets nor in reactivity to mitogens was observed between patients of different clinical stages. However, when the lymphocyte subsets were compared between patients at each stage and the healthy group, decreased percentages of Leu-1+ and Leu-3a+ in patients with stage IV cancer and Leu-2a+ in those with stage I were observed, while the percentage of Leu-11a+ cells was high in stage I and III patients. 4) No difference in lymphocyte subsets in relation to histological type was observed. 5) Among noncancerous respiratory disease patients, there was a reduced percentage of Leu-1+ cells in sarcoidosis and pulmonary emphysema, and reduced percentages of Leu-1+ and Leu-3a+ cells in pulmonary fibrosis and diffuse panbronchiolitis. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
3804783 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
227 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 35,
号 3,
p. 227-236,
発行日 1986-09
|
| 旧ID |
49925 |
HiroshimaJMedSci_35_227.pdf (1.3 MB)
