| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Changes of Histamine Contents and Mast Cell Population in the Gastric Mucosa of Carbon Tetrachloride-Induced Cirrhotic Rats |
|
言語 |
en |
| 作成者 |
SEIKOH, Rokuroh
KODAMA, Osamu
OGAWA, Yoshiteru
ITOH, Nobuaki
TAKEUCHI, Hitoshi
TANAKA, Tsuneo
ICHIBA, Yasuyuki
DOHI, Kiyohiko
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Histamine |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Mast cell |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Cirrhosis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Gastric mucosal lesion |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
For the purpose of clarifying the mechanism of gastric mucosal lesion complicated with liver cirrhosis, the authers examined the changes of histamine contents and mast cell population in the gastric mucosa of carbon tetrachloride-induced cirrhotic rats. The histamine contents in the gastric mucosa and the mast cell count in the superficial area of the mucosa were significantly increased spontaneously and reduced with cold restraint stress in cirrhotic rats. However, no reductions in the both factors were observed in normal rats. The incedence of gastric mucosal lesions in cirrhotic rats was 38%, while it was 0% in normal rats, and rose to 100% in the former against 28% in the latter with stress. The hexosamine contents in the gastric mucosa were significantly lower in cirrhotic rats than in normal rats. It is considered that in cirrhotic rats easy release of gastric mucosal histamine with stress, which is associated with degranulation of mast cells in superficial layer, results in development of gastric mucosal lesions, and that the reduction in defensive capacity may be one of the causes for the increase in mast cells. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
3830996 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
395 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 34,
号 4,
p. 395-397,
発行日 1985-12
|
| 旧ID |
49882 |
HiroshimaJMedSci_34_395.pdf (397.8 KB)
