| アイテムタイプ |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Study of Genetic Effects of Sulphur Mustard Gas on Former Workers of Ohkunojima Poison Gas Factory and Their Offspring |
|
言語 |
en |
| 作成者 |
YAMAKIDO, Michio
NISHIMOTO, Yukio
SHIGENOBU, Takuzo
ONARI, Kiyoshi
SATOH, Chiyoko
GORIKI, Kazuaki
FUJITA, Mikio
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Sulphur mustard gas |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Mutation |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Genetic effects |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Electrophoretic variants |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
General health examination and one-dimensional electrophoretic examination to detect mutations at the protein level were conducted in order to elucidate potential genetic effects of sulphur mustard gas on children of the former workers of Ohkunojima Poison Gas Factory. In the general examination, no disease which was definitely considered to be caused by genetic effects was observed, and no examination values obtained for the children proved to be significantly abnormal compared with those for their parents. Blood samples from 456 children were electrophoretically examined for 30 protein systems. A total of 36 protein variants were detected in 10 protein systems, and the frequency of variants was 2.63 per 1,000 tests. Family study was completed for 32 of these variants, all of which were confirmed to be genetic variants. In 29,868 locus tests, mutation occurred in germ cells of parents could not be detected. Among 36 variants, two PGM2 variants and one GPI variant were detected for the first time in this study. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
4066398 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
311 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 34,
号 3,
p. 311-322,
発行日 1985-09
|
| 旧ID |
49870 |
HiroshimaJMedSci_34_311.pdf (5.3 MB)
