| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Studies of Standard Liver Function and Hepatic Fibrosis in Rats with Obstructive Jaundice and Biliary Drainage |
|
言語 |
en |
| タイトル |
|
|
タイトル |
閉塞性黄疸及び減黄ラットにおける一般肝機能と肝線維化の検討 |
|
言語 |
ja |
| 作成者 |
Takeuchi, Hitoshi
Kodama, Osamu
Ito, Nobuaki
Tanaka, Tsuneo
Harada, Mitsuo
Seikoh, Rokuro
Yamamoto, Masami
Ezaki, Haruo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Hepatic fibrosis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Obstructive jaundice |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Biliary drainage |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
The authors prepared the obstructive jaundice model on which the external biliary drainage was operable, and tried to clarify the critical duration of obstruction from the aspects of the standard liver function and hepatic fibrosis, and the following results were obtained. 1) The T. B, Al-p, GOT and GPT levels in 1 to 4 weeks after the common bile duct obstruction was significantly high (p<0.01) as compared with the normal levels, but no definite differences were found between each period of obstruction. After the biliary drainage was performed for 5 days in each period of obstruction, the GOT level was significantly high (p<0.05) as compared with the normal level in 1, 3 and 4 weeks, but no significantly differences were noted in the T. B, Al-p and GPT levels in 1 to 4 weeks. 2) Classifying the severity of hepatic fibrosis into the scores from 0 to 3, the severity score of hepatic fibrosis indicated higher levels with the prolongation of the common bile duct obstruction, and significant differences were observed between 1 and 2 weeks (p<0.05), and between 3 and 4 weeks (p<0.01). The severity score of hepatic fibrosis after biliary drainage showed significantly lower levels (p<0.05) as compared with the common bile duct obstruction in 1 to 3 weeks. In 4 weeks, however, no significant difference was noted. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6534925 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
679 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 4,
p. 679-683,
発行日 1984-12
|
| 旧ID |
38267 |
HiroshimaJMedSci_33_679.pdf (537.3 KB)
