| Item type |
デフォルトアイテムタイプ_(フル)(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
The High Dose Therapy of Anti-Human Lymphoblast Globulin in Living Related Renal Transplantation |
|
言語 |
en |
| タイトル |
|
|
タイトル |
生体腎移植における抗リンパ芽球グロブリン大量療法 |
|
言語 |
ja |
| 作成者 |
Dohi, Kiyohiko
Fukuda, Yasuhiko
Asahara, Toshimasa
Yahata, Hiroshi
Ono, Eiji
Takenaka, Masaharu
Marubayashi, Seiji
Omotehara, Tamon
Tabe, Yasuji
Eto, Takaaki
Ezaki, Haruo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
AHLG |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Lymphocyte subpopulation |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Kidney transplantation |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Large doses of antihuman lymphoblast globulin (AHLG) were used prophylactically in three recipients of renal allografts from living related donors. These recipients received 1,500 mg/day of AHLG for 14 days beginning on the second day before transplantation in addition to the standard immunosuppression. Serum AHLG levels, serum anti-AHLG antibodies and T cell subsets were checked serially. The results were as follows: 1) No side effects and or complications of AHLG were encountered in these recipients. 2) None of patients treated with AHLG had any rejection episodes within three months after transplantation but after that several rejections occurred in two patients. 3) Maximum serum AHLG concentrations, reached at 10-12 days after transplantation, ranged from 252 mg/dl to 465 mg/dl. Serum AHLG levels were detected at least one month after final injection of AHLG. 4) No patients made detectable antibodies to horse IgG. 5) The values of T cell counts, % T cell and T cell subsets (Leu 3a/2a) varied considerable from patient to patient, in two cases were kept moderately low by AHLG treatment. We concluded that the effect of AHLG on T cell subsets was not distinctive. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Hiroshima University School of Medicine |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
6384144 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0018-2052 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00664312 |
| 開始ページ |
|
|
開始ページ |
223 |
| 書誌情報 |
Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences
巻 33,
号 2,
p. 223-231,
発行日 1984-06
|
| 旧ID |
38205 |