{"created":"2025-02-23T06:16:53.798860+00:00","id":2012866,"links":{},"metadata":{"_buckets":{"deposit":"d24047e8-98a1-42d9-8ae3-e80edaf93dab"},"_deposit":{"created_by":41,"id":"2012866","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2012866"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02012866","sets":["1727147343679:1730442224523:1730442343133"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Effects of Atrophic Changes in Mucosa and Endogenous Gastrin (Hypergastrinemia) on Development of Experimental Gastric Cancer and its Growth in Rats : A Pilot Study","subitem_title_language":"en"},{"subitem_title":"萎縮性胃炎とガストリンの実験胃癌に及ぼす影響","subitem_title_language":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kishimoto, Shinya","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kishimoto","familyNameLang":"en"}],"givenNames":[{"givenName":"Shinya","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kunita, Satoko","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kunita","familyNameLang":"en"}],"givenNames":[{"givenName":"Satoko","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Shimizu, Satoshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Shimizu","familyNameLang":"en"}],"givenNames":[{"givenName":"Satoshi","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Koh, Hassei","creatorNameLang":"en"}],"familyNames":[{"familyName":"Koh","familyNameLang":"en"}],"givenNames":[{"givenName":"Hassei","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Yamamoto, Masahiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Yamamoto","familyNameLang":"en"}],"givenNames":[{"givenName":"Masahiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kajiyama, Goro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kajiyama","familyNameLang":"en"}],"givenNames":[{"givenName":"Goro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Miyoshi, Akima","creatorNameLang":"en"}],"familyNames":[{"familyName":"Miyoshi","familyNameLang":"en"}],"givenNames":[{"givenName":"Akima","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Experimental atropic gastritis","subitem_subject_scheme":"Other"},{"subitem_subject":"Gastric cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Gastrin","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"In the present experiment the influence of atrophic mucosa and resulting endogenous hypergastrinemia on the induction of gastric cancer by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) was examined in male Donryu rats. All rats were fed MNNG in tap water for 6 months and were killed after more 5 months. The incidence of gastric cancer was 55% in rats with atrophic gastritis and hypergastrinemia, which is significantly higher than the incidence of 10 % observed in rats treated with MNNG alone. Gastric cancer was not found in any rats with atrophic gastritis without associating with hypergastrinemia. These data suggest that atrophic mucosa and resulting hypergastrinemia are important in development and growth of gastric cancer in rats.","subitem_description_language":"en"},{"subitem_description":"This work was supported by a grant from the Ministry of Education (1976-1977).","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University School of Medicine"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"213"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1983-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"218","bibliographicPageStart":"213","bibliographicVolumeNumber":"32","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"6618902","subitem_relation_type_select":"PMID"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_32_213.pdf","filesize":[{"value":"724.2 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2012866/files/HiroshimaJMedSci_32_213.pdf"},"version_id":"bcc53605-f577-40ae-a251-3e78448e94ea"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"38342"},"item_title":"Effects of Atrophic Changes in Mucosa and Endogenous Gastrin (Hypergastrinemia) on Development of Experimental Gastric Cancer and its Growth in Rats : A Pilot Study","item_type_id":"40003","owner":"41","path":["1730442343133"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2012866","relation_version_is_last":true,"title":["Effects of Atrophic Changes in Mucosa and Endogenous Gastrin (Hypergastrinemia) on Development of Experimental Gastric Cancer and its Growth in Rats : A Pilot Study"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T02:51:19.205942+00:00"}