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進行膵癌に対する溶連菌製剤 OK-432 の腫瘍内投与
https://hiroshima.repo.nii.ac.jp/records/2012860
https://hiroshima.repo.nii.ac.jp/records/2012860f88a5627-33e0-4732-8c7a-c3a229f992c5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_32_167.pdf (348.2 KB)
|
| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||||
| タイトル | ||||||||||
| タイトル | Intratumoral Administration of Streptococcal Preparation (OK-432) to Advanced Pancreatic Cancer | |||||||||
| 言語 | en | |||||||||
| タイトル | ||||||||||
| タイトル | 進行膵癌に対する溶連菌製剤 OK-432 の腫瘍内投与 | |||||||||
| 言語 | ja | |||||||||
| 作成者 |
Kodama, Motomu
× Kodama, Motomu
× Tanaka, Tsuneo
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| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Intratumoral administration | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Streptococcal preparation | |||||||||
| 主題 | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Pancreatic cancer | |||||||||
| 主題 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 490 | |||||||||
| 内容記述 | ||||||||||
| 内容記述 | Ten patients with advanced, unresectable carcinoma of the pancreas were treated with intratumoral high-dose injections of OK-432 and their therapeutic responses assessed from the clinical standpoint in the past four years since 1977. Following the treatment, 7 (78%) of 9 patients evaluated by the Karnofsky criteria fell under Category I, of whom 2 were classified under I-C. Five patients (50 %) showed performance status scores of≧80 (on the Karnofsky scale) following operation. A substantial to complete relief of pain was achieved in 3 (60 %) of 5 patients who had complained of pain prior to surgery. The average survival period in the group of OK-432-treated patients did not differ significantly from that in a control group. However, a patient in the treated group is still living 13 months after operation. The results indicate that intratumoral high-dose OK-432 therapy is notably effective for prolongation of survival and for relief of pain with rarity and mildness of side effects. | |||||||||
| 言語 | en | |||||||||
| 出版者 | ||||||||||
| 出版者 | Hiroshima University School of Medicine | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 関連情報 | ||||||||||
| 識別子タイプ | PMID | |||||||||
| 関連識別子 | 6618899 | |||||||||
| 収録物識別子 | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0018-2052 | |||||||||
| 収録物識別子 | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA00664312 | |||||||||
| 開始ページ | ||||||||||
| 開始ページ | 167 | |||||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 32, 号 2, p. 167-171, 発行日 1983-06 |
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| 旧ID | 38336 | |||||||||
