{"created":"2025-02-23T06:15:45.505216+00:00","id":2012827,"links":{},"metadata":{"_buckets":{"deposit":"ee31625d-0cf9-4836-84f8-d5ba16b43710"},"_deposit":{"created_by":41,"id":"2012827","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2012827"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02012827","sets":["1727147343679:1730442224523:1730442345537"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Attempts at Cultivation of Mycobacterium leprae in Cell Culture under Regulation of Redox Potential at Environment","subitem_title_language":"en"},{"subitem_title":"酸化還元電位を調整した環境におけるらい菌の細胞培養のこころみ","subitem_title_language":"ja"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsuo, Yoshiyasu","creatorNameLang":"en"}],"familyNames":[{"familyName":"Matsuo","familyNameLang":"en"}],"givenNames":[{"givenName":"Yoshiyasu","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Tatsukawa, Hiroshi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Tatsukawa","familyNameLang":"en"}],"givenNames":[{"givenName":"Hiroshi","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Mycobacterium leprae","subitem_subject_scheme":"Other"},{"subitem_subject":"Cell culture","subitem_subject_scheme":"Other"},{"subitem_subject":"Redox potential","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Cultivation of Mycobacterium leprae in cell culture was attempted under lower redox potential by adding such reducing agents as reduced glutathione, DL-cysteine hydrochloride, and dithiothreitol to culture medium, and by reduced oxygen tension varying the depth of medium or applying agar suspension technique. During a five years' period since 1976, a slight increase in the number of acid-fast bacilli at harvests was occasionally observed. However, the viability of bacilli recovered was unable to be proven by the mouse foot pad method. It is uncertain whether lower redox potential at environment is strictly requested for cultivation of M. leprae.","subitem_description_language":"en"},{"subitem_description":"This work was supported in part by the Japan-US Cooperative Medical Science Program and the Sasakawa Memorial Health Foundation.","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Hiroshima University School of Medicine"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0018-2052","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00664312","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"開始ページ","attribute_value_mlt":[{"subitem_start_page":"141"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1982-06-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"143","bibliographicPageStart":"141","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"Hiroshima Journal of Medical Sciences"},{"bibliographic_title":"Hiroshima Journal of Medical Sciences"}]}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"6752102","subitem_relation_type_select":"PMID"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"HiroshimaJMedSci_31_141.pdf","filesize":[{"value":"229.9 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2012827/files/HiroshimaJMedSci_31_141.pdf"},"version_id":"a6363a20-8bfb-44a6-b398-aee55d2fd6ac"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"38389"},"item_title":"Attempts at Cultivation of Mycobacterium leprae in Cell Culture under Regulation of Redox Potential at Environment","item_type_id":"40003","owner":"41","path":["1730442345537"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2012827","relation_version_is_last":true,"title":["Attempts at Cultivation of Mycobacterium leprae in Cell Culture under Regulation of Redox Potential at Environment"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-06-02T02:50:04.946071+00:00"}