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急性リンパ性白血病患児のナチュラル・キラー(NK)活性について
https://hiroshima.repo.nii.ac.jp/records/2012777
https://hiroshima.repo.nii.ac.jp/records/2012777bf237fdf-502f-4876-96f7-9e72cf248cdc
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HiroshimaJMedSci_30_127.pdf (474.7 KB)
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| Item type | デフォルトアイテムタイプ_（フル）(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2023-03-18 | |||||||
| タイトル | ||||||||
| タイトル | NATURAL KILLER (NK) ACTIVITY IN CHILDREN WITH ACUTE L YMPHOBLASTIC LEUKEMIA | |||||||
| 言語 | en | |||||||
| タイトル | ||||||||
| タイトル | 急性リンパ性白血病患児のナチュラル・キラー(NK)活性について | |||||||
| 言語 | ja | |||||||
| 作成者 |
Tanaka, Yoshito
× Tanaka, Yoshito
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| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| 主題 | ||||||||
| 主題Scheme | NDC | |||||||
| 主題 | 490 | |||||||
| 内容記述 | ||||||||
| 内容記述 | The natural killer (NK) activity against K 562 target cells was explored in 20 children with acute lymphoblastic leukemia (ALL). Three of 5 patients examined at the time of diagnosis had normal NK activity. Two patients, who had more than 80% circulating blasts had significantly low NK activity. The level of NK activity of these 5 patients was inversely proportional to the percentage of blast cells contaminating the effector cell populations. After initiating induction chemotherapy, the NK activity decreased in spite of disappearance of circulating blasts. After complete remission, their NK activity returned to normal levels, and was rather higher than that of onset of the disease. NK activity of 15 children with ALL remaining in continuous complete remission was as high as that of healthy children and healthy adults in spite of intensive maintenance chemotherapy for 1/2 to 4 years. This was thought to be due to intermittent dose-schedule of the maintenance chemotherapy. | |||||||
| 言語 | en | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan. | |||||||
| 出版者 | ||||||||
| 出版者 | Hiroshima University School of Medicine | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| 出版タイプ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0018-2052 | |||||||
| 収録物識別子 | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AA00664312 | |||||||
| 開始ページ | ||||||||
| 開始ページ | 127 | |||||||
| 書誌情報 |
Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 巻 30, 号 2, p. 127-133, 発行日 1981-06-10 |
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| 旧ID | 37368 | |||||||
