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  1. 広島大学の刊行物
  2. Hiroshima Journal of Medical Sciences
  3. 30巻1号

正常及び異常ヒト心の動脈管閉鎖

https://hiroshima.repo.nii.ac.jp/records/2012765
https://hiroshima.repo.nii.ac.jp/records/2012765
ea8ff0c5-648c-49c6-ab62-f008fef5087f
名前 / ファイル ライセンス アクション
HiroshimaJMedSci_30_35.pdf HiroshimaJMedSci_30_35.pdf (4.9 MB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル CLOSURE OF THE DUCTUS ARTERIOSUS IN NORMAL AND MALFORMED HUMAN HEART
言語 en
タイトル
タイトル 正常及び異常ヒト心の動脈管閉鎖
言語 ja
作成者 Imamura, Hajime

× Imamura, Hajime

en Imamura, Hajime

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Okamoto, Naomasa

× Okamoto, Naomasa

en Okamoto, Naomasa

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
主題Scheme NDC
主題 490
内容記述
内容記述 Histopathological studies were made on 9 necropsy specimens of ductus arteriosus with hypoplastic left heart syndrome and I with rubella syndrome. A control group of 40 normal specimens were also studied. In the 17th week of gestation, ductus arteriosus was composed of few elastic fibers, a thick continuous internal elastic lamina and a wide hypocellular area. In the 8th month of gestation, there was a disruption of the internal elastic laminas, partially degeneration on inner layer of the media and circular fashion arrangement of smooth muscle fibers. In the 40th week of gestation, there was a thickening of the intima, a regular arrangement of muscle fibers in the outer layer of the media, cell degeneration between the intima and the outer layer of the media, presence of cleft tissue in the inner and outer layer of the media, an irregular arrangement and a whorl-like muscle nodles in the intermediate layer of the media. In the term fetuses, there was prominent mounds and disruption of the internal elastic lamina, and disintegretion of medial structure.  In a case with rubella syndrome there was an absence of disruption of the internal elastic lamina and of mounds or intimal thickening and presence of abundant elastic fibers in the media as in the aorta. In a case with hypoplastic left heart syndrome the internal lamina was thick and continuous, and no mounds were observed. There was aboundant elastic fibers in the media, while in 5 hearts there was a lower mounds, disruption of internal elastic lamina and relatively well developed elastic fibers in the media. Two hearts with hypoplastic left heart syndrome showed normal ductus arteriosus. Based on the data from this observation it was suggested that congenital structural anomalies of the ducutus arteriosus play an important role in the formation of patent ductus arteriosus.
言語 en
出版者
出版者 Hiroshima University School of Medicine
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0018-2052
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA00664312
開始ページ
開始ページ 35
書誌情報 Hiroshima Journal of Medical Sciences
Hiroshima Journal of Medical Sciences

巻 30, 号 1, p. 35-42, 発行日 1981-03-10
旧ID 37267
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