{"created":"2025-02-21T04:53:04.580949+00:00","id":2009344,"links":{},"metadata":{"_buckets":{"deposit":"2bfb65e2-f5f2-4dd2-876e-cfbdf85a96da"},"_deposit":{"created_by":41,"id":"2009344","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2009344"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02009344","sets":["1730444907710"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Purification of a Lethal Toxin of Edwardsiella tarda","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suprapto, Hari","creatorNameLang":"en"}],"familyNames":[{"familyName":"Suprapto","familyNameLang":"en"}],"givenNames":[{"givenName":"Hari","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Hara, Takaaki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Hara","familyNameLang":"en"}],"givenNames":[{"givenName":"Takaaki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Nakai, Toshihiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Nakai","familyNameLang":"en"}],"givenNames":[{"givenName":"Toshihiro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Muroga, Kiyokuni","creatorNameLang":"en"}],"familyNames":[{"familyName":"Muroga","familyNameLang":"en"}],"givenNames":[{"givenName":"Kiyokuni","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Edwardsiella tarda","subitem_subject_scheme":"Other"},{"subitem_subject":"toxin","subitem_subject_scheme":"Other"},{"subitem_subject":"extracellular product","subitem_subject_scheme":"Other"},{"subitem_subject":"intracellular component","subitem_subject_scheme":"Other"},{"subitem_subject":"Japanese eel","subitem_subject_scheme":"Other"},{"subitem_subject":"ECP","subitem_subject_scheme":"Other"},{"subitem_subject":"660","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"A toxin lethal to fish was purified from extracellular products (ECP) of Edwardsiella tarda by ion exchange chromatography and gel filtration. The purified toxin is a protein having proteolytic activities and lethal toxicity to Japanese eel Anguilla japonica with the LD50 of 1.6µg per g of fish body weight. Molecular weight of the protein was estimated to be 37 kDa by SDS-PAGE. SDS-PAGE, Western blot and imrnunodiffusion analyses revealed that the 37 kDa protein was present in the ECP and ICC (intracellular components) of virulent strains of E. tardy but not in those of avirulent strains, indicating that this toxin plays an important role in the pathogenicity of E. tarda.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"日本魚病学会"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0388-788X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AN00063165","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"Page Start","attribute_value_mlt":[{"subitem_start_page":"203"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"207","bibliographicPageStart":"203","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"魚病研究"},{"bibliographic_title":"Fish Pathology"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"FishPathol_31_203.pdf","filesize":[{"value":"608.7 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2009344/files/FishPathol_31_203.pdf"},"version_id":"c4073f12-2de5-4d5d-82af-2df416b3df67"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"25892"},"item_title":"Purification of a Lethal Toxin of Edwardsiella tarda","item_type_id":"40003","owner":"41","path":["1730444907710"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2009344","relation_version_is_last":true,"title":["Purification of a Lethal Toxin of Edwardsiella tarda"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-02-22T05:22:59.529673+00:00"}