| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Elevated Brachial-Ankle Pulse Wave Velocity Is Associated with Left Ventricular Hypertrophy in Hypertensive Patients after Stroke |
|
言語 |
en |
| 作成者 |
Masugata, Hisashi
Senda, Shoichi
Hoshikawa, Jun
Murao, Koji
Hosomi, Naohisa
Okuyama, Hiroyuki
Inukai, Michio
Himoto, Takashi
Nakatsuka, Yoichi
Imai, Masanobu
Noma, Takahisa
Kohno, Masakazu
Goda, Fuminori
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2010 東北ジャーナル刊行会 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
hypertension |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Stroke |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
brachial-ankle pulse wave velocity |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Echocardiography |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
left ventricular hypertrophy |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
Brachial-ankle pulse wave velocity (baPWV) is widely used as a marker of arterial stiffness, but there are no data regarding the usefulness of measuring baPWV in hypertensive patients after stroke. The purpose of this study was to examine the clinical significance of baPWV by assessing its correlation with echocardiographic parameters in hypertensive patients after stroke. The study enrolled 61 hypertensives after stroke (24 patients with cerebral infarction and 37 with cerebral hemorrhage) and 61 age-matched hypertensives without stroke. Left ventricular (LV) hypertrophy was evaluated by measuring LV mass index (LVMI) and relative wall thickness (RWT), and LV diastolic function was evaluated by measuring peak early mitral annular velocities (E') using echocardiography. Concentric LV hypertrophy showing increased RWT (0.50 ± 0.12) was observed in hypertensives after stroke, but not in hypertensives without stroke. In hypertensives after stroke, elevated baPWV correlated with age (r = 0.60, p < 0.001), systolic blood pressure (r = 0.56, p < 0.001), increased LVMI (r = 0.47, p < 0.001), and decreased E' (r = -0.40, p = 0.002). Multiple regression analysis showed that age (β coefficient = 0.43, p < 0.001), systolic blood pressure (β coefficient = 0.40, p < 0.001), and LVMI (β coefficient = 0.25, p = 0.008) were independent determinants of elevated baPWV. In conclusion, elevated baPWV is more closely associated with LV hypertrophy than with LV diastolic dysfunction. Elevated baPWV is independently associated with the severity of LV hypertrophy adjusted with systolic blood pressure and age in hypertensive patients after stroke. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Tohoku University Medical Press |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1620/tjem.220.177 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1620/tjem.220.177 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0040-8727 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00863920 |
| 開始ページ |
|
|
開始ページ |
177 |
| 書誌情報 |
Tohoku Journal of Experimental Medicine
Tohoku Journal of Experimental Medicine
巻 220,
号 3,
p. 177-182,
発行日 2010
|
| 旧ID |
30404 |
TohokuJExpMed_220_177.pdf (314.6 KB)
