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Pouchitis disease activity index (PDAI) does not predict patients with symptoms of pouchitis who will respond to antibiotics

https://hiroshima.repo.nii.ac.jp/records/2008846
https://hiroshima.repo.nii.ac.jp/records/2008846
5cdbe558-5802-43b7-aaae-531b7297388a
名前 / ファイル ライセンス アクション
SurgeryToday_39_962.pdf SurgeryToday_39_962.pdf (221.3 KB)
Item type デフォルトアイテムタイプ_(フル)(1)
公開日 2023-03-18
タイトル
タイトル Pouchitis disease activity index (PDAI) does not predict patients with symptoms of pouchitis who will respond to antibiotics
言語 en
作成者 Kohyama, Mohei

× Kohyama, Mohei

en Kohyama, Mohei

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Takesue, Yoshio

× Takesue, Yoshio

en Takesue, Yoshio

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Ohge, Hiroki

× Ohge, Hiroki

en Ohge, Hiroki

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Murakami, Yoshiaki

× Murakami, Yoshiaki

en Murakami, Yoshiaki

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Shimamoto, Fumio

× Shimamoto, Fumio

en Shimamoto, Fumio

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Sueda, Taijiro

× Sueda, Taijiro

en Sueda, Taijiro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
権利情報 Copyright (c) 2009 Springer
主題
主題Scheme Other
主題 Pouchitis
主題
主題Scheme Other
主題 Pouchitis disease activity index
主題
主題Scheme Other
主題 Ulcerative colitis
主題
主題Scheme NDC
主題 490
内容記述
内容記述 To evaluate whether the pouchitis disease activity index (PDAI) alone is sufficient to select appropriate treatment plans for ulcerative colitis patients with bowel movement problems following ileal pouch-anal anastomosis (IPAA). The study included 70 patients undergoing an IPAA. For these patients, an evaluation by PDAI was performed prospectively at 1-2 years after the ileostomy closure. When the symptoms relevant to bowel movement appeared, PDAI was evaluated and metronidazole or ciprofloxacin was administered. Pouchitis was diagnosed in patients with PDAI scores of 7 or higher. The patients whose PDAI score was less than 7 and who responded to antibiotic therapy were defined as treatment responders having disease not diagnosed by PDAI (TR-NDPDAI). Pouchitis was diagnosed in 16 of the 70 enrolled patients (22.9%) using the PDAI scoring system. Of these 16 patients, 11 had acute pouchitis and 5 had chronic pouchitis. Twenty-one patients whose PDAI score was less than 7 were symptomatic. Among them, 12 were TR-NDPDAI. In patients with TR-NDPDAI, antibiotic treatment resulted in significant improvements in the PDAI score (P < 0.001) and in clinical symptoms (P < 0.001) after treatment. Antibiotic treatment was effective in a considerable number of ulcerative colitis patients whose PDAI score was less than 7 after IPAA.
言語 en
出版者
出版者 Springer
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
出版タイプ
出版タイプ AO
出版タイプResource http://purl.org/coar/version/c_b1a7d7d4d402bcce
関連情報
関連名称 The original publication is available at www.springerlink.com
関連情報
識別子タイプ DOI
関連識別子 10.1007/s00595-009-3988-7
関連情報
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.1007/s00595-009-3988-7
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0941-1291
収録物識別子
収録物識別子タイプ NCID
収録物識別子 AA10824685
開始ページ
開始ページ 962
書誌情報 Surgery Today
Surgery Today

巻 39, 号 11, p. 962-968, 発行日 2009
旧ID 28855
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