| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Long-Term Prognosis of Patients with Major Depression and Silent Cerebral Infarction |
|
言語 |
en |
| 作成者 |
Yamashita, Hidehisa
Fujikawa, Tokumi
Takami, Hiroshi
Yanai, Ichiro
Okamoto, Yasumasa
Morinobu, Shigeru
Yamawaki, Shigeto
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2010 S. Karger AG, Basel |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
elderly |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
major depression |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
silent cerebral infarction |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
magnetic resonance imaging |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
prognosis |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
dementia |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
|
|
内容記述 |
OBJECTIVE: Many studies have examined the effects of cerebrovascular change on treatment response in geriatric depression. However, few such studies have examined the relationship between cerebrovascular changes and long term prognosis. We examined the effects of cerebrovascular change on the course of geriatric depressive symptoms, dementia rates, and mortality over a follow-up period of approximately 10 years. METHOD: Participants were 84 patients with major depression (age of onset greater than 50 years old); patients suffering from strokes, neurological disorders, and other psychiatric disorders were excluded. MRI findings were used to classify all patients into silent cerebral infarction (SCI) positive (n = 37) or negative groups (n = 47). Patient prognoses were ascertained using a review of clinical charts and over the mail. RESULTS: Only 5% of patients with SCI were able to maintain remission, whereas 36% of those patients without SCI were able to do so. Total duration of depressive episodes was significantly longer in the SCI positive group than in the SCI negative group. In addition, SCI was associated with a higher risk of the onset of dementia. CONCLUSION: The results of this long-term follow-up study demonstrate that the presence of SCI is associated with a relatively poor prognosis for geriatric depression |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Karger |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1159/000319359 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1159/000319359 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0302-282X |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00754878 |
| 開始ページ |
|
|
開始ページ |
177 |
| 書誌情報 |
Neuropsychobiology
Neuropsychobiology
巻 62,
号 3,
p. 177-181,
発行日 2010
|
| 旧ID |
30414 |
Neuropsychobiology_62_177.pdf (68.9 KB)
