| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2025-01-27 |
| タイトル |
|
|
タイトル |
Antibiotic susceptibility and genome analysis of Enterococcus species isolated from inpatients in one hospital with no apparent outbreak of vancomycin-resistant Enterococcus in Japan |
|
言語 |
en |
| 作成者 |
Fujii, Ayumi
Kawada-Matsuo, Miki
Le, Mi Nguyen-Tra
Masuda, Kanako
Tadera, Kayoko
Suzuki, Yujin
Nishihama, Saki
Hisatsune, Junzo
Sugawara, Yo
Kashiyama, Seiya
Shiba, Hideki
Aikawa, Tomonao
Ohge, Hiroki
Sugai, Motoyuki
Komatsuzawa, Hitoshi
|
| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is the peer reviewed version of the following article: Ayumi Fujii et al, Antibiotic susceptibility and genome analysis of Enterococcus species isolated from inpatients in one hospital with no apparent outbreak of vancomycin-resistant Enterococcus in Japan, Microbiology and Immunology, 68, 8, 254-266 (2024), , which has been published in final form at https://doi.org/10.1111/1348-0421.13155. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
This is not the published version. Please cite only the published version. |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antibiotic resistance genes |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antibiotic susceptibility |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Enterococcus |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hospital surveillance |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
PBP5 |
| 主題 |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
vancomycin-resistant Enterococcus |
| 内容記述 |
|
|
内容記述 |
To prevent nosocomial infection, it is important to screen for potential vancomycin-resistant Enterococcus (VRE) among patients. In this study, we analyzed enterococcal isolates from inpatients in one hospital without any apparent outbreak of VRE. Enterococcal isolates were collected from inpatients at Hiroshima University Hospital from April 1 to June 30, 2021 using selective medium for Enterococci. Multilocus sequence typing, antimicrobial susceptibility testing, and whole-genome sequencing were performed. A total of 164 isolates, including Enterococcus faecium (41 isolates), Enterococcus faecalis (80 isolates), Enterococcus raffinosus (11 isolates), Enterococcus casseliflavus (nine isolates), Enterococcus avium (12 isolates), Enterococcus lactis (eight isolates), Enterococcus gallinarum (two isolates), and Enterococcus malodoratus (one isolate), were analyzed. We found one vanA-positive E. faecium, which was already informed when the patient was transferred to the hospital, nine vanC-positive E. casseliflavus, and two vanC-positive E. gallinarum. E. faecium isolates showed resistance to ampicillin (95.1%), imipenem (95.1%), and levofloxacin (87.8%), and E. faecalis isolates showed resistance to minocycline (49.4%). Ampicillin- and levofloxacin-resistant E. faecium had multiple mutations in penicillin-binding protein 5 (PBP5) (39/39 isolates) and ParC/GyrA (21/36 isolates), respectively. E. raffinosus showed resistance to ampicillin (81.8%), imipenem (45.5%), and levofloxacin (45.5%), and E. lactis showed resistance to ampicillin (37.5%) and imipenem (50.0%). The linezolid resistance genes optrA and cfr(B) were found only in one isolate of E. faecalis and E. raffinosus, respectively. This study, showing the status of enterococci infection in hospitalized patients, is one of the important information when considering nosocomial infection control of VRE. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Wiley |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1111/1348-0421.13155 |
| 開始ページ |
|
|
開始ページ |
254 |
| 書誌情報 |
en : Microbiology and Immunology
巻 68,
号 8,
p. 254-266,
発行日 2024-06-14
|
MicrobImm_68_254.pdf (1.1 MB)
