| アイテムタイプ |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2025-01-22 |
| タイトル |
|
|
タイトル |
Association between social background and implementation of postoperative adjuvant chemotherapy for older patients undergoing curative resection of colorectal cancers, sub-analysis of the HiSCO-04 study |
|
言語 |
en |
| 作成者 |
Bekki, Tomoaki
Shimomura, Manabu
Saito, Yasufumi
Nakahara, Masahiro
Adachi, Tomohiro
Ikeda, Satoshi
Shimizu, Yosuke
Kochi, Masatoshi
Ishizaki, Yasuyo
Yoshimitsu, Masanori
Takakura, Yuji
Shimizu, Wataru
Sumitani, Daisuke
Kodama, Shinya
Fujimori, Masahiko
Oheda, Mamoru
Kobayashi, Hironori
Akabane, Shintaro
Yano, Takuya
Ohdan, Hideki
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00384-023-04583-7 |
|
言語 |
en |
| 権利情報 |
|
|
権利情報 |
This is not the published version. Please cite only the published version. |
|
言語 |
en |
| 権利情報 |
|
|
権利情報 |
この論文は出版社版ではありません。引用の際には出版社版をご確認、ご利用ください。 |
|
言語 |
ja |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Colorectal cancer |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Older patients |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Postoperative adjuvant chemotherapy |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Social backgrounds |
| 内容記述 |
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|
内容記述 |
Purpose Adjuvant chemotherapy is recommended following colorectal cancer resection based on risk of recurrence. In older patients, treatment decisions should consider recurrence rates and tolerability, as well as functional prognosis, residual disease, and social factors. This study aims to investigate factors, including social background, influencing implementation of postoperative adjuvant chemotherapy in older patients undergoing curative resection for colorectal cancer. Methods This multi-institutional prospective cohort study included 15 institutions belonging to the Hiroshima Surgical study group for Clinical Oncology. We analyzed 159 older patients aged ≥ 80 years, who underwent curative resection for stage III colorectal cancer between December 2013 and June 2018, as sub-analysis of the HiSCO-04 study. Results In total, 62 (39.0%) patients underwent postoperative adjuvant chemotherapy. Four factors were significantly associated with its implementation: performance status < 2, Charlson Comorbidity Index < 2, prognostic nutritional index ≥ 40, and presence of a spouse or siblings as lifestyle supporters. No significant difference was found in the backgrounds between complete and incomplete postoperative adjuvant chemotherapy patients. Conclusion Performance status, Charlson Comorbidity Index, nutritional status, and presence of a spouse or siblings as lifestyle supporters are possible factors influencing the implementation of postoperative adjuvant chemotherapy in older patients. To select appropriate treatment options, including postoperative adjuvant chemotherapy, it is essential to consider physical condition and comorbidities of older patients, thoroughly explain the situation to their families, and establish a support system to enhance understanding of the available treatment options. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Springer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 関連情報 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1007/s00384-023-04583-7 |
| 開始ページ |
|
|
開始ページ |
11 |
| 書誌情報 |
en : International Journal of Colorectal Disease
巻 39,
p. 11,
発行日 2023-12-28
|
| 旧ID |
56155 |
IJCD_39_11.pdf (473.6 KB)
