{"created":"2025-02-21T03:30:09.440175+00:00","id":2006725,"links":{},"metadata":{"_buckets":{"deposit":"8787f157-cf0f-4117-879e-644e287f1d62"},"_deposit":{"created_by":41,"id":"2006725","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2006725"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02006725","sets":["1730444907710"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Creation of highly functional CO_3Ap-collagen scaffold biomaterials","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Okazaki, Masayuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Okazaki","familyNameLang":"en"}],"givenNames":[{"givenName":"Masayuki","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2010 日本歯科理工学会"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Scaffold biomaterials","subitem_subject_scheme":"Other"},{"subitem_subject":"CO_3Ap-collagen","subitem_subject_scheme":"Other"},{"subitem_subject":"High function","subitem_subject_scheme":"Other"},{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Physicochemical properties of apatites are affected dramatically by the substitution of trace elements. Especially, biological apatites constituting bone and teeth contain several wt% of CO32– ions, which are related to the crystallinity and solubility. Recently, scaffold biomaterials are being developed with a shape-maintaining property in addition to large pores and high porosity, into which cells can easily invade. To develop a new biodegradable scaffold biomaterial, bone-like carbonate apatites (CO3Ap) were synthesized and CO3Ap–collagen scaffolds were created. This scaffold biomaterial is useful for regions with bone regeneration ability. When these sponge-frame complexes with rh-BMP2 were implanted beneath the periosteum cranii of rats, sufficient new bone was created at the surface of the periosteum cranii after 4 weeks' implantation. Furthermore, when a CO3Ap-collagen sponge containing SVVYGLR peptide was implanted as a graft into a tissue defect created in rat tibia, the migration of numerous vascular endothelial cells, as well as prominent angiogenesis inside the graft, could be detected after 1 week. Thus, the modification of higher functions such as cytokine and angiogenesis factors is effective for low regeneration regions using tissue engineering biomaterials.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Japanese Society for Dental Materials and Devices"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0287-4547","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA10443149","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"Page Start","attribute_value_mlt":[{"subitem_start_page":"1"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"3","bibliographicPageStart":"1","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Dental Materials Journal"},{"bibliographic_title":"Dental Materials Journal"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.4012/dmj.2009-R01","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://dx.doi.org/10.4012/dmj.2009-R01","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://wwwsoc.nii.ac.jp/jsdmd/2010/all2010.html#top29-1","subitem_relation_type_select":"URI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"DentMaterJ_29_1.pdf","filesize":[{"value":"1.2 MB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2006725/files/DentMaterJ_29_1.pdf"},"version_id":"f98d19c8-e913-4fbd-9f12-ff99943f9853"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"30403"},"item_title":"Creation of highly functional CO_3Ap-collagen scaffold biomaterials","item_type_id":"40003","owner":"41","path":["1730444907710"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2006725","relation_version_is_last":true,"title":["Creation of highly functional CO_3Ap-collagen scaffold biomaterials"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-02-21T08:17:49.532118+00:00"}