| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
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|
タイトル |
Corticospinal tract conduction block results in the prolongation of central motor conduction time in compressive cervical myelopathy |
|
言語 |
en |
| 作成者 |
Nakanishi, Kazuyoshi
Tanaka, Nobuhiro
Fujiwara, Yasushi
Kamei, Naosuke
Ochi, Mitsuo
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| アクセス権 |
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|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
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|
権利情報 |
Copyright (c) 2006 Elsevier Ltd. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
motor evoked potentials |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
central motor conduction time |
| 主題 |
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|
主題Scheme |
Other |
|
主題 |
spinal cord evoked potentials |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
cervical myelopathy |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
transcranial magnetic stimulation |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| 内容記述 |
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|
内容記述 |
Objective: The objective of this study was to analyze corticospinal function in patients with compressive cervical myelopathy and to elucidate the mechanism underlying its prolonged central motor conduction time (CMCT). Methods: Motor evoked potentials following transcranial magnetic stimulation (TMS) and peripheral conduction time in the ulnar and tibial nerves following electrical stimulation were measured from the abductor digiti minimi (ADM) and abductor hallucis (AH) muscles in 24 patients with compressive cervical myelopathy and used to calculate CMCT. Spinal cord evoked potentials (SCEPs) following transcranial electric stimulation were recorded intraoperatively from the C2-3 to C6-7 intervertebral levels. Correlations between prolonged CMCT and SCEP values were then estimated. Results: The shorter/longer CMCT between the patients' right and left ADM and AH were 8.5 ± 2.9/11.5 ± 3.3 and 16.2 ± 3.1/18.4 ± 3.3 ms, respectively (mean ± SD). The SCEPs amplitude at C6-7, compared to C2-3, was 25.7 ± 21.0 %.0 The attenuation of SCEP amplitude, but not latency, at C6-7 correlated significantly with CMCT prolongation. Conclusions: Our data support the view that CMCT prolongation is primarily due to corticospinal conduction block, rather than conduction delay. Significance: Insight was provided into the mechanism of corticospinal dysfunction in compressive cervical myelopathy. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Elsevier |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.clinph.2005.11.010 |
| 関連情報 |
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|
識別子タイプ |
PMID |
|
|
関連識別子 |
16442342 |
| 関連情報 |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1016/j.clinph.2005.11.010 |
| 収録物識別子 |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1388-2457 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA11309888 |
| 開始ページ |
|
|
開始ページ |
623 |
| 書誌情報 |
Clinical Neurophysiology
Clinical Neurophysiology
巻 117,
号 3,
p. 623-627,
発行日 2006-03
|
| 旧ID |
17055 |
ClinNeur_117_623.pdf (361.4 KB)
