{"created":"2025-02-21T03:28:01.747872+00:00","id":2006659,"links":{},"metadata":{"_buckets":{"deposit":"bdf2d442-af5f-4994-a7a1-402d2d350584"},"_deposit":{"created_by":41,"id":"2006659","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2006659"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02006659","sets":["1730444907710"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Physicochemical Cause and Effect Observed in DNA Length-Dependent Division of Protocell as the Primitive Flow of Information","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsuo, Muneyuki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Matsuo","familyNameLang":"en"}],"givenNames":[{"givenName":"Muneyuki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kurihara, Kensuke","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kurihara","familyNameLang":"en"}],"givenNames":[{"givenName":"Kensuke","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Toyota, Taro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Toyota","familyNameLang":"en"}],"givenNames":[{"givenName":"Taro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Suzuki, Kentaro","creatorNameLang":"en"}],"familyNames":[{"familyName":"Suzuki","familyNameLang":"en"}],"givenNames":[{"givenName":"Kentaro","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sugawara, Tadashi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Sugawara","familyNameLang":"en"}],"givenNames":[{"givenName":"Tadashi","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"© 2020 Matsuo M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited."}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Protocell","subitem_subject_scheme":"Other"},{"subitem_subject":"Self-reproduction","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA-chain length","subitem_subject_scheme":"Other"},{"subitem_subject":"Primitive flow of information","subitem_subject_scheme":"Other"},{"subitem_subject":"Physicochemical causes and effects","subitem_subject_scheme":"Other"},{"subitem_subject":"Morphological change","subitem_subject_scheme":"Other"},{"subitem_subject":"Lipo-deoxyribozyme","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"In the prebiotic era, physicochemical cause and effect served as the primitive flow of information for protocells. Our recent study claimed that the manners and frequencies of self-reproduction of giant vesicle (GV) -based model protocells were regulated by the incorporated DNA-length, and not the base-pair sequence due to the presence of a supramolecular catalyst (lipo-deoxyribozyme) composed of DNA and lipophilic catalysts. The DNA-length dependent dynamics of the self-reproducing GVs containing different length of DNA were examined by three independent experiments; Population analysis by flow cytometric measurements, counting of　increased numbers of protocells and direct morphological observation of a single GV by confocal microscopy. These results may shed light on the information system in the prebiotic stage, when the central dogma was not established. Notably, recent reports have revealed the possible influence of DNA length on the activation of living cells through the complexation of DNA to an enzyme in non-sequential aggregation manner.","subitem_description_language":"en"},{"subitem_description":"This work was supported by JSPS KAKENHI (Grant Numbers JP25103009, JP16K05759 and JP17H04876), ‘Platform for Dynamic Approaches to Living System’ at the University of Tokyo, Kanagawa University Grant for Joint Research, and the Yoshida Scholarship Foundation.","subitem_description_type":"Other"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Longdom Publishing"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"2471-2663","subitem_source_identifier_type":"ISSN"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-10-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"Clinical & Medical Biochemistry"},{"bibliographic_title":"Clinical & Medical Biochemistry"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.35248/2471-2663.20.06.150","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.35248/2471-2663.20.06.150","subitem_relation_type_select":"DOI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"ClinMedBiochem_Matsuo_2020.pdf","filesize":[{"value":"315.4 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2006659/files/ClinMedBiochem_Matsuo_2020.pdf"},"version_id":"24a56483-b7c7-4370-9ab0-b68bbd9db294"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"51564"},"item_title":"Physicochemical Cause and Effect Observed in DNA Length-Dependent Division of Protocell as the Primitive Flow of Information","item_type_id":"40003","owner":"41","path":["1730444907710"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2006659","relation_version_is_last":true,"title":["Physicochemical Cause and Effect Observed in DNA Length-Dependent Division of Protocell as the Primitive Flow of Information"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-02-21T08:06:41.892415+00:00"}