| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Water-Solubilization of Fullerene Derivatives by β-(1,3-1,6)-D-Glucan and Their Photodynamic Activities toward Macrophages |
|
言語 |
en |
| 作成者 |
Ikeda, Atsushi
Iizuka, Tatsuya
Maekubo, Naotake
Nobusawa, Kazuyuki
Sugikawa, Kouta
Koumoto, Kazuya
Suzuki, Toshio
Nagasaki, Takeshi
Akiyama, Motofusa
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2017 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim |
| 権利情報 |
|
|
権利情報 |
This is the peer reviewed version of the following article: A. Ikeda, T. Iizuka, N. Maekubo, K. Nobusawa, K. Sugikawa, K. Koumoto, T. Suzuki, T. Nagasaki, M. Akiyama, Water-Solubilization of Fullerene Derivatives by β-(1,3-1,6)-D-Glucan and Their Photodynamic Activities toward Macrophages, Chem.-Asian J., 12, 1069–1074, 2017, which has been published in final form at https://doi.org/10.1002/asia.201700182. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| 権利情報 |
|
|
権利情報 |
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。 |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
fullerenes |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
host-guest chem. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
macrophage |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
medicinal chem. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
polysaccharides |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
430 |
| 内容記述 |
|
|
内容記述 |
Anionic and neutral fullerene derivatives were dissolved in water by β-(1,3-1,6)-D-glucan (β-1,3-glucan) as a solubilizing agent. In the water-solubilized complexes, the concentrations of fullerene derivatives were ca. 0.30 mM and the average particle sizes were ca. 90 nm. The β-1,3-glucan complexed fullerene derivative with a carboxylic acid was found to have higher photodynamic activity toward macrophages under visible-light irradiation (λ > 610 nm) when compared with that of other β-1,3-glucan-complexed fullerene derivatives. This result suggests that carboxylic acid moieties in the complex enhance the binding affinity with β-1,3-glucan-receptors on the surface of macrophages when β-1,3-glucan is recognized. In contrast, all β-1,3-glucan complexed fullerene derivatives showed no photodynamic activity toward HeLa cells under the same conditions. |
|
言語 |
en |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
This work was supported by JSPS KAKENHI Grant-in-Aid for Scientific Research (B) (Grant No. JP16H04133) and Grant-in-Aid for Challenging Exploratory Research (Grant No. JP16K13982). |
| 出版者 |
|
|
出版者 |
Wiley-VCH |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1002/asia.201700182 |
| 関連情報 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
28266184 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1861-4728 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1861-471X |
| 開始ページ |
|
|
開始ページ |
1069 |
| 書誌情報 |
Chemistry - An Asian Journal
Chemistry - An Asian Journal
巻 12,
号 10,
p. 1069-1074,
発行日 2017-05-18
|
| 旧ID |
46208 |
CAJ_12-10_1069.pdf (1.3 MB)
