| Item type |
デフォルトアイテムタイプ_（フル）(1) |
| 公開日 |
2023-03-18 |
| タイトル |
|
|
タイトル |
Pressure dependence of the apparent specific volume of bovine serum albumin : Insight into the difference between isothermal and adiabatic compressibilities |
|
言語 |
en |
| 作成者 |
Gekko, Kunihiko
Araga, Mariko
Kamiyama, Tadashi
Ohmae, Eiji
Akasaka, Kazuyuki
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
権利情報 |
Copyright (c) 2009 Elsevier B. V. |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Isothermal compressibility |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Adiabatic compressibility |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Bovine serum albumin |
| 主題 |
|
|
主題Scheme |
Other |
|
主題 |
Specific volume |
| 主題 |
|
|
主題Scheme |
NDC |
|
主題 |
460 |
| 内容記述 |
|
|
内容記述 |
There are some theoretical arguments related to interpreting the adiabatic compressibility (beta(s)) of a protein determined from the sound velocity and the difference between beta(s) and isothermal compressibility (beta(T)). To address these problems experimentally, we constructed a high-pressure oscillating densitometer and used it to measure the apparent specific volume of bovine serum albumin as a function of pressure (0.1-78 MPa) and temperature (5-35 degrees C). The beta(T) determined from plots of the apparent specific volume vs. pressure was slightly larger than beta(s) at all temperatures examined, with the difference between the two compressibilities increasing as the temperature was decreased. Only at room temperature did the observed beta(T) agree with those estimated from beta(s) using the heat capacity and the thermal expansibility of the protein, suggesting that there are significant as-yet-unknown mechanisms that affect protein compressibility. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Elsevier Science BV |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
AO |
|
出版タイプResource |
http://purl.org/coar/version/c_b1a7d7d4d402bcce |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.bpc.2009.06.008 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
http://dx.doi.org/10.1016/j.bpc.2009.06.008 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0301-4622 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00566073 |
| 開始ページ |
|
|
開始ページ |
67 |
| 書誌情報 |
Biophysical Chemistry
Biophysical Chemistry
巻 144,
号 1-2,
p. 67-71,
発行日 2009-09
|
| 旧ID |
28874 |
BiophysChem_144_67.pdf (219.5 KB)
