{"created":"2025-02-21T03:19:22.563745+00:00","id":2006373,"links":{},"metadata":{"_buckets":{"deposit":"651b3121-cf89-4cf4-8621-52aeeed5d89f"},"_deposit":{"created_by":41,"id":"2006373","owners":[41],"pid":{"revision_id":0,"type":"depid","value":"2006373"},"status":"published"},"_oai":{"id":"oai:hiroshima.repo.nii.ac.jp:02006373","sets":["1730444907710"]},"author_link":[],"item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"Regulation of c-myc through intranuclear localization of its RNA subspecies","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Noriaki","creatorNameLang":"en"}],"familyNames":[{"familyName":"Shimizu","familyNameLang":"en"}],"givenNames":[{"givenName":"Noriaki","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Kawamoto, June-ko","creatorNameLang":"en"}],"familyNames":[{"familyName":"Kawamoto","familyNameLang":"en"}],"givenNames":[{"givenName":"June-ko","givenNameLang":"en"}]},{"creatorNames":[{"creatorName":"Utani, Koh-ichi","creatorNameLang":"en"}],"familyNames":[{"familyName":"Utani","familyNameLang":"en"}],"givenNames":[{"givenName":"Koh-ichi","givenNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"Access Rights","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2007 Elsevier Inc."}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"nucleolus","subitem_subject_scheme":"Other"},{"subitem_subject":"RNA FISH","subitem_subject_scheme":"Other"},{"subitem_subject":"nuclear structure and function","subitem_subject_scheme":"Other"},{"subitem_subject":"post-transcriptional gene regulation","subitem_subject_scheme":"Other"},{"subitem_subject":"c-myc","subitem_subject_scheme":"Other"},{"subitem_subject":"460","subitem_subject_scheme":"NDC"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"We used fluorescence in situ hybridization (FISH) to detect c-myc RNA subspecies in human COLO 320DM tumor cells. Although the FISH procedure removed the majority of RNAs from the nucleolus, c-myc RNA continued to be detected in both the nucleoplasm and nucleolus. This finding suggests stable association between c-myc RNA and the nucleolus. Nucleolar accumulation of c-myc RNA appeared to be temporally regulated by cell cycle progression. Hybridization with exon- and strand-specific RNA probes indicated that the non-protein coding exon 1 plays a novel role in determining the subnuclear localization of c-myc RNA. Antisense RNA targeting exon 2 localized only with nucleoplasmic foci, where it might interact with the sense strand. Thus, c-myc gene expression may be regulated by intranuclear localization of its RNA.","subitem_description_language":"en"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"Academic Press Inc Elsevier Science"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"0006-291X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"AA00564395","subitem_source_identifier_type":"NCID"}]},"item_1617187024783":{"attribute_name":"Page Start","attribute_value_mlt":[{"subitem_start_page":"806"}]},"item_1617187056579":{"attribute_name":"Bibliographic Information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-08-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"810","bibliographicPageStart":"806","bibliographicVolumeNumber":"359","bibliographic_titles":[{"bibliographic_title":"Biochemical and Biophysical Research Communications"},{"bibliographic_title":"Biochemical and Biophysical Research Communications"}]}]},"item_1617258105262":{"attribute_name":"Resource Type","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"Version Type","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_b1a7d7d4d402bcce","subitem_version_type":"AO"}]},"item_1617353299429":{"attribute_name":"Relation","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.bbrc.2007.05.201","subitem_relation_type_select":"DOI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://dx.doi.org/10.1016/j.bbrc.2007.05.201","subitem_relation_type_select":"DOI"}}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-03-18"}],"displaytype":"simple","filename":"BBRC_359-3_806.pdf","filesize":[{"value":"325.3 KB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hiroshima.repo.nii.ac.jp/record/2006373/files/BBRC_359-3_806.pdf"},"version_id":"3d7a424d-a9d6-4843-8307-5b8f55141e3a"}]},"item_1732771732025":{"attribute_name":"旧ID","attribute_value":"20744"},"item_title":"Regulation of c-myc through intranuclear localization of its RNA subspecies","item_type_id":"40003","owner":"41","path":["1730444907710"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-03-18"},"publish_date":"2023-03-18","publish_status":"0","recid":"2006373","relation_version_is_last":true,"title":["Regulation of c-myc through intranuclear localization of its RNA subspecies"],"weko_creator_id":"41","weko_shared_id":-1},"updated":"2025-02-21T07:27:15.745695+00:00"}