2026-03-13T13:53:45Z https://hiroshima.repo.nii.ac.jp/oai

oai:hiroshima.repo.nii.ac.jp:02006654 2025-02-21T08:06:14Z 1730444907710

Coronary Calcium Score as a Predictor for Coronary Artery Disease and Cardiac Events in Japanese High-Risk Patients Yamamoto, Hideya Ohashi, Norihiko Ishibashi, Ken Utsunomiya, Hiroto Kunita, Eiji Oka, Toshiharu Horiguchi, Jun Kihara, Yasuki Cardiovascular disease mortality Coronary angiography Coronary calcification 490 Background: Although the coronary artery calcium (CAC) score as measured with computed tomography (CT) is associated with cardiovascular mortality and morbidity in Western countries, little is known in Asian populations. Methods and Results: Three hundred and seventeen Japanese patients (205 men and 112 women) were followed in the study and they underwent both coronary angiography and CT for CAC measurements. The frequencies of angiographic coronary artery disease (CAD) were 5%, 36%, 76%, 80%, and 94% (P<0.001) and the needs for revascularization were 5%, 26%, 53%, 59%, and 69% (P<0.001) in patients with CAC scores of 0 (n=64), 1-100 (n=58), 101-400 (n=76), 401-1,000 (n=70), and >1,000 (n=49), respectively. In the average of 6.0 (range, 1-10) years follow-up period, 34 patients died including 13 from reasons of cardiac disease. In a Cox proportional hazard model after adjustment for age and sex, traditional coronary risk factors, previous myocardial infarction, and the need for revascularization, the hazard ratio for cardiac mortality in patients with a CAC score >1,000 was 2.98 (95% confidence interval: 1.15-9.40) compared with those with a CAC score=0-100. Conclusions: The CAC score has a predictive value for angiographical CAD and long-term mortality from cardiac disease in Japanese high-risk patients who undergo coronary angiography. (Circ J 2011; 75: 2424-2431) http://purl.org/coar/resource_type/c_6501 一般社団法人日本循環器学会 2011 VoR 1346-9843 AA11591968 2424 Circulation Journal 10 75 2431 2424 Circulation Journal https://hiroshima.repo.nii.ac.jp/records/2006654 eng 10.1253/circj.CJ-11-0087 http://dx.doi.org/10.1253/circj.CJ-11-0087 open access Copyright (c) 2011 The Japanese Circulation Society.