2026-03-13T05:06:27Z https://hiroshima.repo.nii.ac.jp/oai

oai:hiroshima.repo.nii.ac.jp:02013792 2025-06-02T03:33:26Z 1727147343679:1730442224523:1730442230828

Transabdominal Ultrasound Real-time Tissue Elastography as a Screening Method for Early Chronic Pancreatitis Shimizu, Akinori Shimizu Akinori Ishii, Yasutaka Ishii Yasutaka Serikawa, Masahiro Serikawa Masahiro Tsuboi, Tomofumi Tsuboi Tomofumi Kurihara, Keisuke Kurihara Keisuke Tatsukawa, Yumiko Tatsukawa Yumiko Kawamura, Ryota Kawamura Ryota Tsushima, Ken Tsushima Ken Saito, Yuhei Saito Yuhei Sekito, Tsuyoshi Sekito Tsuyoshi Nakamura, Shinya Nakamura Shinya Hirano, Tetsuro Hirano Tetsuro Fukiage, Ayami Fukiage Ayami Mori, Takeshi Mori Takeshi Ikemoto, Juri Ikemoto Juri Chayama, Kazuaki Chayama Kazuaki open access Copyright (c) 2019 Hiroshima University Medical Press Chronic Pancreatitis Elasticity Imaging Techniques Ultrasonography Endosonography Pancreatic Diseases Early Medical Intervention Background and Purpose: The concept of early chronic pancreatitis was proposed in Japan with the aim to improve the prognosis of patients with chronic pancreatitis. Endoscopic ultrasonography plays an important role in early diagnoses, but is limited by its invasiveness and poor objectivity. Hence, this study aimed to determine the usefulness of transabdominal ultrasound real-time tissue elastography as a screening method for early chronic pancreatitis. Methods: We retrospectively examined 73 patients who underwent simultaneous ultrasound real-time tissue elastography and endoscopic ultrasonography from 2011 to 2014. The correlation between feature values (MEAN, %AREA, COMP) calculated by real-time tissue elastography and the Rosemont classification of endoscopic ultrasonography diagnostic criteria for chronic pancreatitis, and the diagnostic ability of ultrasound real-time tissue elastography to recognize “indeterminate for chronic pancreatitis" findings, which correspond to early chronic pancreatitis, were evaluated. Main Results: Based on the Rosemont classification, 26 patients were “normal", 16 were “indeterminate for chronic pancreatitis", 13 were “suggestive of chronic pancreatitis", and 18 were “consistent with chronic ancreatitis". There were significant correlations between the feature values (MEAN, %AREA, COMP) and the Rosemont classification (p < 0.001; ρ = –0.788, 0.779, and 0.489, respectively). The area under the curve for the ability of MEAN to diagnose “indeterminate for chronic pancreatitis" was 0.889 (sensitivity, 93.8%; specificity, 76.9%). Conclusions: The feature values calculated by ultrasound real-time tissue elastography were correlated with the Rosemont classification. Ultrasound real-time tissue elastography may be a useful screening method for early chronic pancreatitis. Hiroshima University Medical Press 2019-09 eng departmental bulletin paper VoR https://hiroshima.repo.nii.ac.jp/records/2013792 10.24811/hjms.68.2-3_35 https://doi.org/10.24811/hjms.68.2-3_35 0018-2052 2433-7668 AA00664312 Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 68 2-3 35 35 41 https://hiroshima.repo.nii.ac.jp/record/2013792/files/HiroshimaJMedSci_68_35.pdf 831.8 KB