2026-03-06T02:05:52Z https://hiroshima.repo.nii.ac.jp/oai

oai:hiroshima.repo.nii.ac.jp:02013628 2025-06-02T03:23:50Z 1727147343679:1730442224523:1730442260662

Well-differentiated Endocrine Cell Carcinoma of Ileum Treated by Laparoscopy-assisted Surgery : A Case Report Sasada, Shinsuke Sasada Shinsuke Ojima, Yasutomo Ojima Yasutomo Nishizaki, Masahiko Nishizaki Masahiko Harano, Masao Harano Masao Matsukawa, Hiroyoshi Matsukawa Hiroyoshi Aoki, Hideki Aoki Hideki Shiozaki, Shigehiro Shiozaki Shigehiro Ohno, Satoshi Ohno Satoshi Ninomiya, Motoki Ninomiya Motoki Matsuura, Hiroo Matsuura Hiroo Takakura, Norihisa Takakura Norihisa open access (c) Hiroshima University Medical Press. Small intestinal tumor Endocrine cell carcinoma Laparoscopy-assisted surgery 490 A 72-year-old woman presented at our hospital with a 1-year history of intermittent right lower abdominal pain. Colonoscopic examination revealed a submucosal tumor with a pitted surface in the terminal ileum. Histopathological diagnosis of the carcinoid tumor was made following biopsy. Blood serotonin and urine 5-hydroxy-indoleacetic acid levels were normal, and carcinoid syndrome was not detected. Enhanced abdominal computed tomography scan and 18F-fluorodeoxyglucose positron emission tomography failed to detect multiple lesions, lymph node swelling or distant metastasis. Laparoscopy-assisted ileocecal resection with lymph node dissection was performed. The resected specimen showed a submucosal tumor with a pitted surface 11 x 11 mm in size, located at the terminal ileum. Histopathological examination revealed a well-differentiated endocrine cell carcinoma with an invasion depth to the muscularis propria. Immunohistochemical analysis showed the tumor cells to be chromogranin A and CD56-positive. The patient had no sign of recurrence for 16 months. Hiroshima University Medical Press 2010-06 eng departmental bulletin paper VoR https://hiroshima.repo.nii.ac.jp/records/2013628 0018-2052 AA00664312 Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 59 2 35 35 38 https://hiroshima.repo.nii.ac.jp/record/2013628/files/HiroshimaJMedSci_59_35.pdf 5.6 MB