2026-03-12T11:23:10Z https://hiroshima.repo.nii.ac.jp/oai

oai:hiroshima.repo.nii.ac.jp:02012836 2025-06-02T02:50:49Z 1727147343679:1730442224523:1730442343955

Basic Study of Polyetherurethane Coated Bead-Type Activated Charcoal for Direct Hemoperfusion ポリエーテル型ウレタン被覆ビーズ状活性炭を用いた血液直接灌流の基礎研究 Kawanishi, Hideki Kawanishi Hideki Nishiki, Masayuki Nishiki Masayuki Sugiyama, Masafumi Sugiyama Masafumi Cho, Tsuneo Cho Tsuneo Tsuchiya, Taro Tsuchiya Taro Ezaki, Haruo Ezaki Haruo open access Liver support system Activated charcoal Polyetherurethane Hemoperfusion 490 A new type of activated charcoal for the direct hemoperfusion (DHP) has been developed for use in treatment of fulminant hepatic failure. Bead-type activated charcoal from petroleum pitch (BAC) was coated with polyetherurethane. The coating has permitted the charcoal to minimize the number of released microparticles and yet to show nearly the same adsorption performance as that of the non-coated BAC in vitro adsorption test. DHP using a fulminant hepatic failure dog induced by hepatic ischemia has shown improved consciousness and good biocompatibility as well as good clearance of toxic substances. As above, the newly developed bead-type activated charcoal coated with polyetherurethane can be considered effective in treatment of fulminant hepatic failure. Hiroshima University School of Medicine 1983-03 eng departmental bulletin paper VoR https://hiroshima.repo.nii.ac.jp/records/2012836 6863016 0018-2052 AA00664312 Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 32 1 9 9 14 https://hiroshima.repo.nii.ac.jp/record/2012836/files/HiroshimaJMedSci_32_9.pdf 623.3 KB