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oai:hiroshima.repo.nii.ac.jp:02007779 2025-02-21T10:57:41Z 1730444907710

Increased corticospinal excitability during direct observation of self-movement and indirect observation with a mirror box Funase, Kozo Funase Kozo Tabira, Takayuki Tabira Takayuki Higashi, Toshio Higashi Toshio Liang, Nan Liang Nan Kasai, Tatsuya Kasai Tatsuya open access Copyright (c) 2007 Elsevier Ireland Ltd Mirror neuron system Mirror box Corticospinal excitability TMS SEP 460 To explore the effect of mirror box therapy based on the mirror neuron (MN) system of the primary motor cortex (M1), we examined if direct (without a mirror) and indirect (with a mirror) observation of self-movement in healthy subjects induced changes in motor evoked potential (MEP) evoked by transcranial magnetic stimulation. MEPs were elicited from the first dorsal interosseous and the flexor carpi radialis muscles. Somatosensory evoked potential (SEP) during self-movement observation were also recorded. Both observations of self-movement with and without a mirror increased MEP amplitude. In addition, increase in MEP amplitude was specific to the prime mover muscle involved in the observed movement. The SEPs increased similar to the MEPs during both observations of self-movement with and without a mirror. We conclude that although the MN system can be activated by observing self-movement in a manner similar to that achieved by observing movement of another person, there were no detectable effect on corticospinal excitability that were specific to movements observed with a mirror. Elsevier Ireland Ltd 2007-03-29 eng journal article AO https://hiroshima.repo.nii.ac.jp/records/2007779 10.1016/j.neulet.2007.04.025 http://dx.doi.org/10.1016/j.neulet.2007.04.025 0304-3940 AA00754925 Neuroscience Letters Neuroscience Letters 419 2 108 108 112 https://hiroshima.repo.nii.ac.jp/record/2007779/files/NeuLet_419-2_108.pdf 138.0 KB