2026-03-11T04:23:08Z https://hiroshima.repo.nii.ac.jp/oai

oai:hiroshima.repo.nii.ac.jp:02013276 2025-02-26T04:56:35Z 1727147343679:1730442224523:1730442322118

Study of Portal Arterialization with Auxiliary Liver in Rats Hong, He-Qun Hong He-Qun Asahara, Toshimasa Asahara Toshimasa Ito, Hisao Ito Hisao Watanabe, Hiroshi Watanabe Hiroshi Kimura, Atsuo Kimura Atsuo Urushihara, Takashi Urushihara Takashi Marubayashi, Seiji Marubayashi Seiji Fukuda, Yasuhiko Fukuda Yasuhiko Nishiki, Masayuki Nishiki Masayuki Dohi, Kiyohiko Dohi Kiyohiko open access Rat liver Portal arterialization Heterotopic auxiliary transplantation 490 The effect of portal arterialization was examined in 20 heterotopic auxiliary rat livers. Portal blood was supplied from recipient iliac artery (0.58 mm in diameter) connected to the donor portal vein using the cuff technique. Portal hypertension caused by arterial blood pressure resulted in the immediate operative death by bleeding in four of the rats (20%) from the spontaneous rupture of the graft capsule. Severe graft congestion was noticed at autopsy 3-14 days after transplantation in 13 rats. Massive portal and sinusoidal congestion and focal hemorrhagic necrosis were confirmed by pathological examination. The results of our study demonstrate that the portal arterialization used in the auxiliary rat liver transplantation would not be applicable unless the optimal hemodynamic condition is warranted. Hiroshima University Medical Press 1991-03 eng departmental bulletin paper VoR https://hiroshima.repo.nii.ac.jp/records/2013276 1864764 0018-2052 AA00664312 Hiroshima Journal of Medical Sciences Hiroshima Journal of Medical Sciences 40 1 29 29 33 https://hiroshima.repo.nii.ac.jp/record/2013276/files/HiroshimaJMedSci_40_29.pdf 945.6 KB