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oai:hiroshima.repo.nii.ac.jp:02003149 2025-02-19T11:42:41Z 1730444908512:1730444911739

Association between resistance-associated NS5A variants of hepatitis C virus and efficacy of direct-acting antivirals in human hepatocyte transplanted mice 1) Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice 2) Limitations of daclatasvir/asunaprevir plus beclabuvir treatment in cases of NS5A inhibitor treatment failure ヒト肝細胞キメラマウスを用いたNS5A阻害薬耐性変異型HCVとDAA療法の関連性の研究 1) NS5A阻害薬治療不成功例におけるNS5A耐性関連変異およびヒト肝細胞キメラマウスを用いたNS5A-P32欠失変異を持つC型肝炎ウイルスに対する有効な治療法の検討 2) NS5A阻害薬治療不成功例におけるダクラタスビル/アスナプレビル/ベクラブビル治療の問題点について 寺岡, 雄吏 Teraoka, Yuji 寺岡 Teraoka 雄吏 Yuji open access (c) 2018 Elsevier Inc. All rights reserved. (c) 2018 The Authors eng doctoral thesis https://hiroshima.repo.nii.ac.jp/records/2003149 Biochemical and Biophysical Research Communications 500 (2018) 152e157 Teraoka et al., Journal of General Virology 2018;99:1058-1065 https://doi.org/10.1016/j.bbrc.2018.04.005 https://doi.org/10.1099/jgv.0.001091 甲第7998号 博士(医学) Doctor of Philosophy in Medical Science 2019-09-20 広島大学 Hiroshima University https://hiroshima.repo.nii.ac.jp/record/2003149/files/k7998_1.pdf 469.9 KB https://hiroshima.repo.nii.ac.jp/record/2003149/files/k7998_2.pdf 518.5 KB https://hiroshima.repo.nii.ac.jp/record/2003149/files/k7998_3-1.pdf 469.0 KB